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Research themes

Suggested starting points, not a ranking

Pick a theme to see consortia, centres, companies, playbooks and calls whose official text mentions it. Each item is listed because its official text (or the call text on this site) mentions this theme: the matching sentence and its source are shown. Grouped by how open the route is, alphabetical within each group. This is not a ranking of companies or organisations.

All research themes

Continuous crystallization2 sourced items1 consortium, 1 playbook Polymorph and solid form control4 sourced items2 consortia, 2 playbooks Impurity rejection and purification2 sourced items1 consortium, 1 playbook Particle engineering7 sourced items3 consortia, 1 playbook, 1 call, 1 company page, 1 calendar item PAT and process modelling (incl. AI/ML-assisted process development)7 sourced items1 consortium, 1 playbook, 2 calls, 3 company pages Flow chemistry4 sourced items1 consortium, 1 call, 2 company pages Biocatalysis2 sourced items2 company pages Green and sustainable process15 sourced items5 consortia, 1 playbook, 2 calls, 5 company pages, 2 calendar items Microgravity crystallization1 sourced item1 call Continuous manufacturing9 sourced items5 consortia, 2 playbooks, 2 company pages

Counts are sourced items (consortia, playbooks, calls, company pages and calendar entries), not a count of consortia only. Suggested starting points, not a ranking.

Step by step from a theme to consortia, playbooks and calls: Start-here guide.

Continuous crystallization (2 items)
Crystallizing continuously (MSMPR cascades, tubular or oscillatory-baffled crystallizers) rather than in batches.
Polymorph and solid form control (4 items)
Polymorphs, salts, cocrystals, hydrates and solvates, and keeping the right solid form through the process.
Impurity rejection and purification (2 items)
Rejecting or purging impurities, and purification steps in drug-substance processes.
Particle engineering (7 items)
Particle size, shape and properties through crystallization, milling, drying and powder processing.
PAT and process modelling (incl. AI/ML-assisted process development) (7 items)
Process analytical technology, in-line monitoring, mechanistic and data-driven models, and AI/ML for process development.
Flow chemistry (4 items)
Reactions run in continuous flow (flow reactors, microreactors, telescoped flow synthesis).
Biocatalysis (2 items)
Enzymes and engineered biocatalysts in chemical synthesis.
Green and sustainable process (15 items)
Green chemistry and engineering, solvent and waste reduction, process mass intensity.
Microgravity crystallization (1 items)
Crystallization experiments in microgravity, on the ISS or other orbital platforms.
Continuous manufacturing (9 items)
End-to-end or unit-level continuous processing of drug substance and drug product.