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Pitching industry on precompetitive enabling technology

Our guidance on framing a proposal around scale-up, robustness, cost, sustainability and publication, with the public tools and statements it draws on. Checked 30 Oct 2026 · 6 of 8 sources rechecked automatically, unchanged as of 12 Nov 2026.

Themes: Green and sustainable process

From official sources

Public tools and statements this guidance draws on

  • ETC defines pre-competitive projects as "collaborations between multiple pharmaceutical companies and third parties" designed to produce an efficiency-enhancing advancement.[1]
  • The ACS GCI Pharmaceutical Roundtable describes PMI as developed "to benchmark and quantify improvements towards greener manufacturing processes", and offers a free PMI Calculator.[2]
  • Its Solvent Selection Tool covers 272 solvents, with health, environmental and ICH solvent information.[3]
  • The Roundtable says its tools are "vetted by Roundtable companies prior to their public release".[4]
  • Merck describes setting molecule-aware PMI targets for API processes with its SMART PMI tool.[5]
  • GSK says it has published guides on the environmental impact of different solvents and reagents.[6]
  • Pfizer's partnering page lists, for its modular continuous platforms, a desired "significant reduction in scale-up and technology transfer efforts".[7]
  • Lilly's LRAP is described as pre-competitive so that results can be published jointly.[8]

Our guidance

The Grant Lattice's own suggestions, not a statement by any funder, company or centre.

  • Scale-up: show what you have demonstrated at which scale, what you expect to change at the next scale, and what data would settle it.
  • Robustness: give operating ranges, known failure modes and how you would detect them (for example with in-line measurement).
  • Cost: state savings in steps, equipment, time or materials in numbers a process team can check.
  • Sustainability: report PMI with the Roundtable's calculator and justify solvent choices with a published solvent guide, rather than using general claims.
  • Precompetitive publication: say up front what will be published, what stays with each party, and use non-proprietary model compounds where you can.
  • Keep the first contact non-confidential; agree confidentiality terms before sharing unpublished data.

Have an idea, need to network? Tell us Early-career researchers: share a research idea and who you’d like to reach. We read every submission; it’s not a guarantee of an introduction.

Sources (8)

  1. About us (etconsortium.org) · etconsortium.org · checked 30 Oct 2026
  2. Process Mass Intensity (ACS GCI Pharmaceutical Roundtable) · acsgcipr.org · checked 30 Oct 2026
  3. Solvent Selection Tool (ACS GCI Pharmaceutical Roundtable) · acsgcipr.org · checked 30 Oct 2026
  4. Tools (ACS GCI Pharmaceutical Roundtable) · acsgcipr.org · checked 30 Oct 2026
  5. Green chemistry programs and initiatives (merck.com) · www.merck.com · checked 30 Oct 2026
  6. Climate (gsk.com) · www.gsk.com · checked 30 Oct 2026
  7. Research and Business Development Partnerships (pfizer.com) · www.pfizer.com · checked 30 Oct 2026 (by hand; the site does not allow automated checks)
  8. Lilly Research Award Program (LRAP) (lilly.com) · www.lilly.com · checked 30 Oct 2026 (by hand; the site does not allow automated checks)

Always confirm on the official page.